WebAll lanes : Anti-Cleaved PARP1 antibody (ab4830) at 1/1000 dilution Lane 1 : Jurkat cell lysate Lane 2 : Jurkat cells treated with Etoposide (1 µM for 16 hours) Lanes 3 & 5 : HeLa cell lysate Lane 4 : HeLa cells treated with Etoposide (1 µM for 16 hours) Lane 6 : HeLa cells treated with Staurosporine (3 µM for 16 hours) Lysates/proteins at 40 µg per lane. WebCleaved PARP Monoclonal Antibody: 免疫原: 合成多肽: 宿主: 小鼠: 反应性: 人: 应用: WB: 实验建议: 最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比 …
PARP (Cleaved) Monoclonal Antibody - ChemicalBook
WebJan 23, 2007 · In absence of activation signal, PARP1 is autoinhibited by the PARP alpha-helical domain (also named HD region), which prevents effective NAD +-binding (PubMed:26626479, PubMed:26626480, PubMed:32241924). ... Cleaved into 2 chains. Poly [ADP-ribose] polymerase 1, processed C-terminus Curated. Web在凋亡早期,Caspase-3作用于PARP,使其裂解为89 kD和24 kD 2个片段,修复作用丧失。 其中89 kD片段产生后会游出细胞核,因而89 kD可以作为细胞发生凋亡检测的一个指标,可以用 ProteinFind ®Anti-PARP Mouse … the society room at hartford
PARP1 (cleaved Asp214, Asp215) Polyclonal Antibody
WebPARP is composed of four domains of interest: a DNA-binding domain, a caspase-cleaved domain (see below), an auto-modification domain, and a catalytic domain. The DNA-binding domain is composed of two zinc finger motifs. In the presence of damaged DNA (base pair-excised), the DNA-binding domain will bind the DNA and induce a conformational ... WebPARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress (1). This protein can be cleaved by many ICE-like caspases in vitro (2,3) and is one of … WebJul 10, 2001 · The poly(ADP-ribose) polymerase (PARP-1), a 113 kDa nuclear enzyme, is cleaved in fragments of 89 and 24 kDa during apoptosis. This cleavage has become a useful hallmark of apoptosis and has been ... myrea mayer